Interventional Endocrinology · San Diego

Parathyroid Ablation

For selected patients with a parathyroid adenoma who are not candidates for surgery, image-guided RFA or ethanol ablation offers a minimally invasive, off-label option to reduce parathyroid hormone production.

Parathyroid & other neck lesions

Selected off-label applications for patients who are not surgical candidates.

The same image-guided techniques used for thyroid nodules — radiofrequency ablation and ethanol ablation — can, in carefully selected cases, be applied to other neck lesions. The most established of these is the parathyroid adenoma.

A parathyroid adenoma is a small, benign growth of a parathyroid gland that causes primary hyperparathyroidism. Surgery — parathyroidectomy — remains the standard, definitive treatment. But some patients are not candidates for an operation, whether because of other medical conditions, prior neck surgery, anesthesia risk, or personal choice. For these patients, ultrasound-guided RFA or ethanol ablation of a localized adenoma may be considered as an off-label, minimally invasive option intended to reduce parathyroid hormone production and its effects.

These are off-label applications: they are not FDA-cleared indications, the evidence base is more limited than for thyroid nodule ablation, and they are appropriate only after careful evaluation and a multidisciplinary discussion. Candidacy depends on precise localization of the adenoma, its relationship to surrounding structures, and confirmation that ablation is a reasonable choice for that individual. Other selected benign neck lesions may also be evaluated for ablation on a case-by-case basis.

If you have a parathyroid adenoma or another neck lesion and are not a candidate for surgery — or simply want to understand whether a non-surgical approach is reasonable for you — we are glad to review your imaging and laboratory results and talk it through.

Not a candidate for parathyroid surgery?

We are glad to review your imaging and labs. Start with an evaluation at Diabetes & Endocrine Specialists to discuss whether ablation is reasonable for you.

Request an evaluation